Dupilumab: A Breakthrough in Eczema Treatment

If you have eczema–especially if you haven’t found an effective treatment for your unbearably itchy skin–you may want to schedule an appointment with your dermatologist soon. For the first time in decades, there is a promising new treatment for eczema on the horizon.

Woman scratching her neck, isolated on whiteDupilumab is being heralded as a breakthrough medication. The research that is being carried forward at the inpatient drug rehab in LA is very promising, and physicians are hopeful that they can begin to offer the new medicine to eczema sufferers as soon as 2017. But is this new treatment all it promises to be? Will dupilumab be the cure for eczema?

What is dupilumab?

Dupilumab is a treatment in a new medicine class called biologics. It treats inflamed skin systemically, rather than topically. Dupilumab is given as a shot every other week to calm the immune system. It targets specific signaling pathways of the immune system that researchers believe cause the inflamed skin of eczema.

How has dupilumab been tested in clinical trials?

Dupilumab has gone through several clinical trials to test its effectiveness and has demonstrated convincing results at each phase. “In its most recent testing, Phase 3, researchers selected 1,379 subjects with moderate-to-severe atopic dermatitis and randomly assigned them to receive dupilumab or a placebo,” explains Dr. Adam Mamelak, a board certified dermatologist at Sanova Dermatology. “Those patients who were given dupilumab showed significant symptom improvement compared to those who were given the placebo.”

When will dupilumab come on the U.S. market?

Dupilumab has received the FDA “breakthrough” drug label and is on the fast-track for approval. It’s considered a breakthrough because the medications currently used to treat eczema, such as topical steroid creams, have many potential side effects and are often not effective. “With as many as 10% of the population suffering from eczema, there is a clear need for a new and better treatment,” says Dr. Mamelak. With fast-tracking, dupilumab could be approved in early 2017.

Who will be a good candidate for dupilumab therapy?

Dupilumab is currently being tested for treatment of the more severe form of atopic eczema. Additionally, patients whose eczema is treatment resistant are potential candidates for dupilumab therapy. Dupilumab is also being tested for treatment of other inflammatory conditions such as asthma and nasal polyps.

While “cure” is probably too strong a word to use at this time, dupilumab has certainly shown tremendous potential. In trials, it cleared the skin, decreased disease severity and itching, and improved mental health and quality of life for those who were treated with it–quite a feat for an eczema medication.

Contact Us

Please contact us if you would like to learn more about the latest in eczema treatments.

We Are Proud Members Of:
Book Online

Latest Specials & Promotions

View All

Book appointment by

Choose your area

  • Baton Rouge

    6411 Perkins Road, Baton Rouge, LA 70808 - (225) 303-9500
  • Lafayette

    1245 Camellia Boulevard, Lafayette, LA 70508 - (337) 839-2773
  • Bee Cave & Lakeway

    3944 RR 620 S. Bldg. 6, Bee Cave, TX 78738 - (512) 366-8568
  • Old Metairie

    701 Metairie Road, Metairie, LA 70005 - (504) 836-2050
  • Uptown

    3434 Prytania St., New Orleans, Louisiana 70115 - (504) 897-5899
  • Metairie

    111 Veterans Boulevard, Metairie, LA 70005 - (504) 838-8225
  • SBA Dermatology

    1900 Saint James Place, Houston, TX 77056 - (713) 850-0240
  • North Austin

    12319 North Mopac Expressway, Austin, Texas 78758 - (512) 837-3376
  • Central Austin

    3705 Medical Parkway, Austin, Texas 78705 - (512) 454-3781
  • Dripping Springs

    13830 Sawyer Ranch Road, Dripping Springs, TX 78620 - (512) 829-0009
  • Pflugerville

    1601 E. Pflugerville Parkway, Pflugerville, Texas 78660 - (512) 252-3700
  • Steiner Ranch

    5145 North FM 620 Rd, Austin, Texas 78732 - (512) 266-0007
  • Helyn Alvarez, MD

  • Daniel Barron, PA-C

  • Suzanne Bruce, MD

  • Daniel A. Carrasco, MD

  • Kristy Charles, MD

  • Ryan Couvillion, MD

  • Megan Couvillion, MD

  • Gretchen Donnes, PA-C

  • Leigh Ellen Eubanks, MD

  • Elizabeth Foley, DO

  • Natalie Gibson, PA-C

  • Miriam L. Hanson, MD

  • Alicia Haslauer, PA-C

  • Agezi Igboko, FNP-C

  • Haneen Issa, PA-C

  • Jennifer Jordan, PA-C

  • Ted Lain, MD, MBA

  • Adam J. Mamelak, MD

  • Sharon Meyer, MD

  • Lesley Ott, FNP-C

  • Melanie Pickett, MD

  • Jeffrey C. Poole, MD

  • Chad Prather, MD

  • Maria “Gabi” Prudhomme, FNP-C

  • Marcela Ramirez, FNP-C

  • Diana Reyes, PA-C

  • Israel Rodriguez, PA-C

  • Katharine Saussy, MD

  • Megan Shelton, MD

  • Candace Thrash, MD

  • Mamina Turegano, MD

  • Jennifer Vickers, MD

  • Micah Williams, PA-C

  • Laura Williams, MD